The osteonecrosis treatment market, based on geography, is segmented into North America (US, Canada, and Mexico), Europe (Germany, France, Italy, UK, Russia, and Rest of Europe), Asia Pacific (Australia, China, Japan, India, South Korea, and Rest of Asia Pacific), Middle East & Africa (South Africa, Saudi Arabia, UAE, and Rest of Middle East & Africa), and South & Central America (Brazil, Argentina, and Rest of South & Central America).
Rising Cases of Orthopedic Injuries and Increasing Geriatric Population Drive Osteonecrosis Treatment Market Growth
According to statistics published by Clevelandclinic.org in 2021, 10,000–20,000 Americans are diagnosed with avascular necrosis (AVN) annually, with the condition affecting individuals of all ages and genders. Nearly 20% of people who experience hip dislocation develop AVN. The cases of osteonecrosis are rising globally owing to the increasing number of bone and joint injuries caused by fatal accidents. Although osteonecrosis more commonly affects the hip, it can also hamper the condition of the humerus, knee, and talus. As per an article published by StatPearls in 2023, AVN causes 10% of hip arthroplasties in the US, mostly in people aged 30–65. A displaced hip or knee might cut off blood supply to the leg. As a result, the tissues in the leg may not receive enough blood (a condition known as ischemia) and may die (a condition known as necrosis). Elbow or upper arm fractures can occasionally impede blood flow to the forearm, creating similar complications. When blood supply to a bone is interrupted, a portion of the bone may die, causing osteonecrosis. As per the article published by PubMed Central in January 2022, a cohort study was carried out including 170,934 major trauma patients. The study concluded that 78.0% of the major trauma patients with traumatic hip dislocations were injured in road traffic accidents, particularly in motor vehicle accidents (49.9%).
Older people are more likely to experience osteonecrosis as they are more prone to bone degeneration and fractures. In an article published by PubMed in 2020, a study was carried out to assess the effectiveness of cannulated internal fixation in long-term outcomes in 73 patients with femoral neck fracture (FNF), alongside identifying the risk factors affecting outcomes. The study results showed that out of these, 7 (i.e., ~10%) experienced femoral head necrosis and 4 of them underwent hip replacement. According to World Health Organization (WHO), 1 in 6 people across the world would be aged 60 years or over by 2030, with an estimated 1.4 billion people being over the age of 60. Therefore, the burgeoning geriatric population and growing awareness about bone health favor the osteonecrosis treatment market.
Osteonecrosis Treatment Market: Segmental Overview
The “Global Osteonecrosis Treatment Market” is segmented on the basis of treatment type, end user, and geography. Based on product type, the market is bifurcated into drugs and surgeries. In terms of end user, the osteonecrosis market is segmented into hospitals, specialty clinics, ambulatory surgical centers, and others.
Osteonecrosis Treatment Market: Competitive Landscape and Key Developments
Major players in the osteonecrosis treatment market include Novartis AG; Teva Pharmaceutical Industries Ltd.; Zimmer Biomet; Pfizer Inc.; Stryker; Exactech, Inc.; Merck & Co. Inc.; Dr. Reddy’s Laboratories Ltd.; Viatris Inc; and Horizon Therapeutics plc. These leading players focus on expanding and diversifying their market presence and clientele, thereby tapping business opportunities prevailing in the osteonecrosis treatment market.
A few of the key developments by major market players are as Follows:
- In May 2022, Regrow Biosciences received an Orphan Drug Designation (ODD) for OSSGROW from the USFDA as well as the European Medicines Agency (EMA). The drug is intended for patients who are suffering from osteonecrosis.
- In April 2021, ECI Pharmaceuticals LLC signed an exclusive distribution agreement with AiPing Pharmaceuticals, Inc. The agreement enabled AiPing to handle the sales, marketing, and distribution of ibuprofen 400 mg, 600 mg, 800 mg tablets, and folic Acid 1 mg tablets in the US.
- In February 2021, Additive Orthopedics received FDA approval for the total talus replacement implant designed as a humanitarian-use device for the talus spacer for the patient-specific treatment of avascular necrosis of the talus in the US.